Ashley H. Tse

Biomedical engineering

Hometown: Phoenix, Arizona, United States

Graduation date: Spring 2023

Ashley Tse
Health icon, disabled. A red heart with a cardiac rhythm running through it.

FURI | Fall 2021

Engineering of Light-Based Promoters with PACE and eVOLVER Continuous Culture Hardware

Phage-assisted continuous evolution (PACE) is a revolutionary new method to rapidly engineer new genes and proteins, but the method requires extensive automation and expensive chemical inducers for precise control of gene expression. The researcher is developing an advanced method of synthetic gene regulation for process control, using optogenetics. By integrating light-based gene circuits with custom hardware for directed evolution, optogenetics allows for precise fine-tuning of PACE for versatile and scalable applications.

Mentor:

Additional projects from this student

Using light-based controls for continuous evolution of genes of interest will make protein engineering capable of faster development cycles.

Mentor:

  • FURI
  • Summer 2021

The SolarSPELL library for biomedical equipment technicians provides offline, digital user manuals, repair guides and more for resource-constrained hospitals.

Mentor:

  • Guest Researcher
  • Spring 2020

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