Laparotomies surgeries are performed to explore and examine a patient’s abdominal cavity to diagnosis any issues or complications a patient may present with. An issue with laparotomy surgeries is maintaining accurate visibility in the abdominal cavity. Along with the current abdominal retractors, lap pads are often crudely used as a cushioning and isolation device. The proposed solution to these issues arising from lap pad use is through the creation of a silicon mesh netting that is malleable, serializable and able to be attached to a retractor being used, providing a decrease surgery time and in organ damage.
The objective of this research is to create an injectable liquid embolic that can degrade as tissue is regenerated for the treatment of cerebral aneurysms. To achieve this, a Michael Addition is formed upon injection of Poly(N-Isopropilacrylamide-co-GAPGLF Acrylate) [Poly(NIPAAm-co-GAPGLF-Ac] and pentaetythritol tetrakis 3-mercaptopriopionate [QT] at 37°C with a neutral pH, resulting in a gelation. Due to the gelation occurring, the copolymer proves to be an ideal candidate for a liquid embolic that is deliverable in water, is hydrophobic, and can degrade a based on enzymes from regenerating tissue.