Glenna Bea Embrador

Biomedical engineering

Hometown: Phoenix, Arizona

Graduation date: Spring 2020

Portrait of Glenna Embrador
Health icon, disabled. A red heart with a cardiac rhythm running through it.

MORE | Spring 2020

Utilizing Histone Deacetylase Inhibitors (HDACi) to Alleviate Traumatic Brain Injury (TBI) Pathology

Following traumatic brain injury (TBI), the body initiates pro-inflammatory responses which in excess, may lead to neurodegeneration. Recent studies report histone deacetylases (HDAC) as a key player in modulating neuroinflammation, rendering it as an attractive target for TBI therapeutics. Current HDAC inhibitors (HDACi) has shown efficacious treatment in cancer applications by modulating gene expressions of cancerous cells. However, there has been limited research selecting the most effective and potent HDACi for TBI applications. This project aims to test the efficacy of HDACi in reducing neuroinflammation in vitro using human astrocyte cultures.

Mentor:

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Additional projects from this student

Optimizing nanoscale antibody protein production pipelines will help better treat traumatic brain injury and develop nanoparticle therapeutics.

Mentor:

  • FURI
  • Spring 2019

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