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Engineering  |  FURI

Blake Browning

Hometown: Scottsdale, Arizona | Graduation Date: Spring 2019
Biomedical Engineering

Treatment of Acute Upper Gastrointestinal Clots Through Histotripsy

Mentor: Vincent Pizziconi
KEEN: Spring 2019

Acute upper gastrointestinal bleeding results in 20,000 deaths annually in the United States. The current issue is in locating and removing an excessive amount of blood clots obstructing the location and visualization of the wound resulting in invasive procedures and multiple blood transfusions. This device is composed of a focused transducer that emits high-intensity focused ultrasound in a method know as histotripsy to induce cavitation to break blood clots in a controlled and localized manner. The device would allow for direct access to the wound without removal of the surrounding clots thus saving time and expense. Future work would include introducing a cooling unit and a control arm.

Other Projects

Side-Viewing Photoacoustic and Ultrasound Imaging Probe

Mentor: Barbara Smith
FURI: Fall 2018

The objective of this research is to develop a side viewing photoacoustic (PA) and ultrasound (US) imaging probe for biomedical applications. Utilizing borosilicate glass capillary tubes as both optical and acoustic waveguides allows for development of PA/US endoscopy probes with diameters much smaller than traditional PA/US endoscopy probes. This decrease in diameter of the PA/US endoscopy probe may facilitate minimally invasive imaging in the human body. In this work, the researchers custom 3D printed an acoustic/optical combiner to enable light and sound to travel efficiently through the hollow waveguide, while a custom-built rotation system enables 360-degree imaging.

Side-Viewing Photoacoustic and Ultrasound Imaging Probe

Mentor: Barbara Smith
FURI: Spring 2018

The objective of this research is to develop a side viewing photoacoustic (PA) and ultrasound (US) imaging probe for biomedical applications. Utilizing borosilicate glass capillary tubes as both optical and acoustic waveguides allows for PA/US endoscopy probes with diameters much smaller than traditional PA/US endoscopy probes. This decrease in size of the PA/US endoscopy probe will allow for minimally invasive imaging in the human body. A custom 3D printed acoustic/optical combiner enables light and sound to travel efficiently through the hollow waveguide, while a custom-built rotation system allows for 360-degree imaging.