Cyanobacteria are photoautotrophs that can be developed as sustainable platforms for production of various biochemical products. To determine the growth pattern a growth curve was created for a cyanobacterium Synechocystis sp. PCC 6803 in different glass vessels. Further, to improve their photosynthetic efficiency, the cells were refactored with the photosynthetic protein genes. Positive colonies were determined using colony PCR. The ultimate goal is to select the most efficiently growing transformant, which can be further engineered for commercially valuable biochemical/s.