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Engineering  |  FURI
FURI Fall 2018
Sustainability

Metabolically Engineering D-Lactate from Corynebacterium Glutamicum

Plastics used today are manufactured from oil, coal, and natural gas. They contribute to environmental pollution. An alternative cost-effective bioplastic, “polylactic acid,” can be produced from D-lactate and L-lactate. D-lactic acid is the uncommon isomer and is not produced in high-levels by microorganisms. Corynebacterium glutamicum was metabolically engineered to produce D-lactate from biomass. C. glutamicum was cultured with aromatics, such as vanillin, vanillic acid, and coumarate that are present in biomass hydrolysates and will be analyzed for the presence of D-lactate. Future research will include the construction of a few more engineered strains for increased production of D-lactic acid.

Portrait of Nauroth, Ben

Ben Nauroth

Cave Creek, Arizona

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