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Understanding the Self-assembly of Metal-organic Supra-molecules

Supra-molecules are large “hollow” molecules typically composed of small rigid metal-organic (MO) frameworks which have many potential applications such as gas separation and storage, as well as targeted drug delivery. Due to the rigidity of the underlying MO frameworks, a supra-molecule usually possesses a well-defined polyhedral shape. The research team will assess how the self-assembly

In situ SEM testing for Fatigue Crack Growth: Mechanical Investigation of Titanium

The objective of this project is to characterize crack growth that occurs in titanium alloys, specifically Grade 5 Ti-6Al-4V, by applying cyclic tensile loading and measuring the crack growth and crack tip opening displacement (CTOD) of specimens at loading ratios of 0.1, 0.3, and 0.5. This project defines the relationship between rate of crack growth

Modeling Extra Cellular Matrix (ECM) Re-organization Due to Cell-ECM Mechanical Interactions

This research focused on the systematic investigation of cell-ECM mechanical interactions through quantitative examination of 165 high-resolution time-lapse data of multi-cellular systems of collective cell migration. The researcher then focused on developing a computational model simulating the dynamic force network in ECM generated by contracting cells. The interaction model of cancer cell protrusions, and the