Varicose veins affect about 20% of the United States’ population at some point in their lives, causing swelling, blue or purple discoloration, cramping, itching, and burning. The goal of this project is to develop a wrap to fit all sizes that provides gradual and continuous pressure to assist the body’s natural mechanisms in reducing these symptoms.
The research objective is to fabricate tunable electrospun nanoscaffolds and analyze their morphology to determine if it is feasible to design an implantable 3D substrate to induce tissue regeneration. Prototypical implantable scaffolds were fabricated from a polymer solution that was propelled via an electric field under set conditions to form electrospun fibers. Scanning electron microscopy
One common flaw in plastic medical instruments is warping and other defects which occurs during the injection or molding process. The objective of this research is to create a model of the strains and stresses induced during the manufacturing process of plastics due to the geometry of the instrument. This model can be used to
In 2014, pressure ulcers affected approximately 2.5 million people in the United States. These blisters form in bony prominences in bed-bound patients. If untreated, these ulcers worsen until they become infected with complications. Current devices to prevent pressure ulcers fail to individualize patient treatment. The research team thus proposes the Pressure Ulcer Monitoring and Prevention
Fabricating and analyzing tunable nanoscaffolds could lead to implants that induce tissue regeneration.
Bioengineering the cell microenvironment is critical when developing cell-based therapeutic devices for regenerative medicine. The focus of this project is to characterize the micromechanical properties of 3D porous electrospun nanoscaffolds intended to serve as cell substrates and aimed to match an individual’s anatomy and tissue regenerative capacity. Nanoscaffolds electrospun from hydrogel polymer solutions were nanomechanically