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Using 1H MRI Reporter S-Gal® to Study Senescent and Quiescent Cells

Senescent and quiescent cells are cells that stop proliferating due to a variety of factors, including stress-induced senescence. Recognizing these cells through MR imaging can help detect dormant  cancer tumors. It has been shown that an enzyme called β-galactosidase (β-gal) is upregulated in senescent and quiescent cells.The combination of S-gal® and ferric ammonium citrate (FAC)

Clinical Imaging Post-Processing to Improve Surgery in Focal Cortical Dysplasia Cases

Focal cortical dysplasia (FCD) is a brain malformation that commonly causes seizures and can be removed in epilepsy surgery. Automated techniques were implemented to detect FCD within a clinical MRI that can guide surgical remediation. This project developed a post-processing pipeline of structural MRI (T1 and FLAIR) to quantify local cortical deformation and grey-white blurring