Kaushal Rege

Ligand-functionalized Microbeads for Preferential Binding of Methylated and Unmethylated DNA

Modifying microbeads with different lipid ligands to modulate their hydrophobicity will improve libraries for gene expression control.

Program: FURI

Engineering Novel Microbead Encapsulated Three Dimensional Tumor and Stem Cell Models for Regenerative Medicine

Amikabead-based encapsulation could lead to effective and long-term delivery of bioactives to the three-dimensional cell spheroids.

Program: MORE

Engineering an Encapsulated 3D Tumor Dormancy Model In Vivo Using NRAS-Mutant Melanoma Cells

Tumor cells cultured in the form of spheroids and encapsulated in polymers can provide insight into studying their in-vitro dormancy.

Program: KEEN, MORE

DNA Repair Capacity of NRAS-Mutant Melanoma 3D Spheroids Under Oxidative Stress and DNA Repair Inhibition

Developing a novel cancer treatment for resistant types of melanoma will help improve therapeutic strategies.

Program: KEEN, MORE

Radiation Induced Polymerization of an Acrylate-Based Compound

Developing a compound that polymerizes when exposed to radiation will further safety measures for radiation toxicity and contamination.

Program: FURI

Investigating Cancer Cell Death and Cell-Signaling Pathways using HSP90 Inhibition and APE1 Inhibition

Program: MORE

Adaptation of Laser Activated Sutures for Intestinal Surgeries via Chemical Cross-linking

Program: FURI

Aminoglycoside Polymers in Combination Treatments for Triple Negative Breast Cancer (TNBC) Studies

Program: MORE