Radiation toxicity is a significant problem that affects the livelihood of people. On the macroscale, nuclear spillage and contamination in areas of habitat can lead to diseases and birth defects in unborn children. On the microscale, inaccuracy in the administration of radiation therapy leads to unintended damage to healthy body tissue. The objective of this
Faculty Mentor: Kaushal Rege
Investigating Cancer Cell Death and Cell-Signaling Pathways using HSP90 Inhibition and APE1 Inhibition
Studying drug delivery to melanoma cells in 3D models will help understand melanoma survival pathways and provide new treatments.
Adaptation of Laser Activated Sutures for Intestinal Surgeries via Chemical Cross-linking
This project seeks to adapt previously developed laser-activated sutures for use in intestinal surgeries. Previous work in this area developed laser activated sutures that improve wound healing by providing an immediate seal upon activation with a near-infrared laser. This project will help address the issue of common, life threatening complications involving intestinal surgeries due to
Aminoglycoside Polymers in Combination Treatments for Triple Negative Breast Cancer (TNBC) Studies
Each year in Arizona, breast cancer causes two deaths and more than 4,600 diagnosed cases. Triple-negative breast cancer is diagnosed in 30% of breast cancer cases. This research involves the formulation of novel nanoparticle vehicles to effectively bind to DNA sites, stop cancer cell proliferation, and prevent cells from reviving. In the initial experiments, the
