A Comparison of CRISPR/Cas-Derived Genome Editing Methods for hPSCs
Studying the characteristics of multiple gene editing systems will establish the optimal workflow for editing stem cells.
David Brafman
Total projects: 10
Projects
Creation of AD-Relevant Isogenic Lines with CasMasTREE
The creation of AD-relevant isogenic lines through gene editing methods can lead to the cure/treatment of Alzheimer's disease.
Brycelyn Whitman
FURI: Needs Review, Summer 2020
Adaptable Multi-Modality Nanoprobes for Non-Invasive Real-Time Monitoring of Engineered Cells and Tissues
Accurate assessment of cell and tissue viability in biomanufacturing will improve research in disease modelling, drug screening and health.
Albert Essuman
FURI: Summer 2020
Creation of AD-Relevant Isogenic Lines with CasMasTREE
The creation of AD-relevant isogenic lines, using the method CasMasTREE, will progress the possible cure for Alzheimer's disease.
Brycelyn Whitman
FURI: Summer 2020
Verification of Ratiometric pH Sensing PHPMA-Derived Polymer in Human Neuronal Tissue Models.
Characterizing the effect of a ratiometric fluorescent pH sensing nanoprobe in different tissue culture models will help scientists better assess cellular microenvironments.
Salma Leyasi
FURI: Spring 2020
Cas9 Mediated Adenosine Transient Reporter for Editing Enrichment
Enriching for edited stem cells using gene editing tools can generate disease-relevant stem cell lines for disease modeling.
Investigating the Role of SP5 in WNT Signaling Using an In-Vitro Model of Neural Patterning
Investigating the role of SP5 in WNT signaling will help better understand the mechanisms underlying WNT-related human defects.
Esther Sim
GCSP: Spring 2019
Modeling Carriers and Biological Specimen Utility of a Molecular Diagnostic Biosensor for Navajo Neurohepatopathy
Diagnosing Navajo neurohepatopathy will help Phoenix Children’s Hospital better treat patients and potential parents carrying the disease.
Jordan Todd
FURI: Spring 2019
Development of Flourcent Siloxane Nano-probes as an In-Line Assay of Cell and Tissue Function
Developing and optimizing fluorescent nanoprobes to assess the functionality of cell culture and tissue live for better disease models.
Salma Leyasi
FURI: Spring 2019
Development and Assessment of a Diagnostic Tool to Detect and Genotype Navajo Neurohepatopathy
Designing a real-time diagnostic tool for detection and genotyping of Navajo neurohepatopathy will improve treatment cost and time.
Sydney Connor
FURI: Spring 2019
