Studying the characteristics of multiple gene editing systems will establish the optimal workflow for editing stem cells.
Total projects: 10
The creation of AD-relevant isogenic lines through gene editing methods can lead to the cure/treatment of Alzheimer's disease.
Adaptable Multi-Modality Nanoprobes for Non-Invasive Real-Time Monitoring of Engineered Cells and Tissues
Accurate assessment of cell and tissue viability in biomanufacturing will improve research in disease modelling, drug screening and health.
The creation of AD-relevant isogenic lines, using the method CasMasTREE, will progress the possible cure for Alzheimer's disease.
Characterizing the effect of a ratiometric fluorescent pH sensing nanoprobe in different tissue culture models will help scientists better assess cellular microenvironments.
Enriching for edited stem cells using gene editing tools can generate disease-relevant stem cell lines for disease modeling.
Investigating the role of SP5 in WNT signaling will help better understand the mechanisms underlying WNT-related human defects.
Modeling Carriers and Biological Specimen Utility of a Molecular Diagnostic Biosensor for Navajo Neurohepatopathy
Diagnosing Navajo neurohepatopathy will help Phoenix Children’s Hospital better treat patients and potential parents carrying the disease.
Developing and optimizing fluorescent nanoprobes to assess the functionality of cell culture and tissue live for better disease models.
Designing a real-time diagnostic tool for detection and genotyping of Navajo neurohepatopathy will improve treatment cost and time.