David Brafman
SSEBE | Assistant Professor
Total mentored projects: 19
iSearchThe creation of AD-relevant isogenic lines through gene editing methods can lead to the cure/treatment of Alzheimer's disease.
Program: FURI
Accurate assessment of cell and tissue viability in biomanufacturing will improve research in disease modelling, drug screening and health.
Program: FURI
Studying the characteristics of multiple gene editing systems will establish the optimal workflow for editing stem cells.
Program: FURI
Characterizing the effect of a ratiometric fluorescent pH sensing nanoprobe in different tissue culture models will help scientists better assess cellular microenvironments.
Program: FURI
Enriching for edited stem cells using gene editing tools can generate disease-relevant stem cell lines for disease modeling.
Program: MORE
Investigating the role of SP5 in WNT signaling will help better understand the mechanisms underlying WNT-related human defects.
Program: GCSP
Diagnosing Navajo neurohepatopathy will help Phoenix Children’s Hospital better treat patients and potential parents carrying the disease.
Program: FURI
Developing and optimizing fluorescent nanoprobes to assess the functionality of cell culture and tissue live for better disease models.
Program: FURI
Designing a real-time diagnostic tool for detection and genotyping of Navajo neurohepatopathy will improve treatment cost and time.
Program: FURI
Developing a live cell labeling method will help analyze the effectiveness of cell therapies used for Alzheimer’s disease.
Program: FURI
Probing the characteristics that mediate cell-selective vulnerability or resistance will help better understand Alzheimer’s disease onset and progression.
Program: MORE
Developing a human-induced pluripotent stem cell model for Alzheimer’s disease that reflects aging will help understand the underlying mechanisms of the disease.
Program: MORE